| 摘要 |
<p num="1"><br/><br/><br/>This invention relates to novel acetylcysteine compositions in solution, <br/>comprising acetylcysteine and which are substantially free of metal chelating <br/>agents, such as EDTA. Further, this invention relates to methods of making and <br/>using the acetylcysteine compositions. The present compositions and methods <br/>are designed to improve patient tolerance and compliance, while at the same <br/>time maintaining the stability of the pharmaceutical formulation. The <br/>compositions and methods of this invention are useful in the treatment of <br/>acetaminophen overdose, acute liver failure, various cancers, <br/>methacrylonitrile poisoning, reperfusion injury during cardio bypass surgery, <br/>and radiocontrast-induced nephropathy, and can also be used as a mucolytic <br/>agent.<br/></p> |
