发明名称 TLR agonists
摘要 The present invention provides for TLR agonist conjugates (compounds) and compositions, as well as methods of using them. The compounds of the invention are broad-spectrum, long-lasting, and non-toxic combination of synthetic immunostimulatory agents, which are useful for activating the immune system of a mammal, preferably a human and can help direct the pharmacophore to the receptor within the endosomes of target cells and enhance the signal transduction induced by the pharmacophore.
申请公布号 AU2006283524(A1) 申请公布日期 2007.03.01
申请号 AU20060283524 申请日期 2006.08.21
申请人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 发明人 HOWARD B. COTTAM;MICHAEL CHAN;CHRISTINA C. N. WU;DENNIS A. CARSON;KENJI TAKABAYASHI
分类号 A61K31/522;C07D473/10 主分类号 A61K31/522
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