发明名称 |
Tillverkning av kromatografimatriser |
摘要 |
The present invention relates to a method of manufacturing a chromatography matrix comprising providing a polysaccharide carrier comprising available hydroxyl groups; and reacting said hydroxyl groups with vinyl sulphonate to provide a sulphonate-functionalized (S-functionalized) cation exchanger. The hydroxyl groups of the carrier may be hydroxyls of the agarose polymer; or alternatively they may be provided on extenders such as polyhydroxyfunctional polymers. In one embodiment, the carrier is made of agarose with improved flow pressure properties. |
申请公布号 |
SE0501936(L) |
申请公布日期 |
2007.03.01 |
申请号 |
SE20050001936 |
申请日期 |
2005.08.31 |
申请人 |
GE HEALTHCARE BIO SCIENCES AB |
发明人 |
AXEN ANDREAS;GLAD GUNNAR;IHRE HENRIK;LARSSON ANDERS;NORRMAN NILS |
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