发明名称 |
Methods of preparing polymers having terminal amine groups |
摘要 |
The present invention is directed to methods of preparing linear polymers such as polyalkylene oxides containing a terminal amine in high purity. One preferred method includes reacting a polyalkylene oxide such as polyethylene glycol containing a terminal azide with a phosphine-based reducing agent such as triphenylphosphine or an alkali metal borohydride reducing agent such as sodium borohydride in a solvent to reflux. The resultant polymer-amines are of sufficient purity so that expensive and time consuming purification steps required for pharmaceutical grade polymers are avoided.
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申请公布号 |
US2007049726(A1) |
申请公布日期 |
2007.03.01 |
申请号 |
US20050291546 |
申请日期 |
2005.12.01 |
申请人 |
ZHAO HONG;RUBIO BELEN;XIA JING |
发明人 |
ZHAO HONG;RUBIO BELEN;XIA JING |
分类号 |
C08G79/02 |
主分类号 |
C08G79/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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