| 发明名称 |
PROCESS FOR PREPARING ANTIBODY MAYTANSINOID CONJUGATES |
| 摘要 |
The invention provides a process for preparing a cell-binding agent chemically coupled to a drug. The process comprises covalently attaching a linker to a cell-binding agent, a purification step, conjugating a drug to the cell-binding agent and a subsequent purification step. |
| 申请公布号 |
CA2794554(A1) |
申请公布日期 |
2007.03.01 |
| 申请号 |
CA20062794554 |
申请日期 |
2006.08.14 |
| 申请人 |
IMMUNOGEN, INC. |
发明人 |
DAI, YONG;WANG, YONG;JIN, SHENGJIN;MESHULAM, DEBORAH H.;AMPHLETT, GODFREY W. |
| 分类号 |
C07K16/18;A61K47/48;C07K1/14 |
主分类号 |
C07K16/18 |
| 代理机构 |
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