发明名称 |
GENE EXPRESSED SPECIFICALLY IN DOPAMINE-PRODUCING NEURON PRECURSOR CELLS AFTER TERMINATION OF DIVISION |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a novel gene expressed specifically and temporarily in dopamine-producing neuron precursor cells immediately after termination of division. <P>SOLUTION: Disclosed is a novel gene 65B13 expressed specifically and temporarily in dopamine-producing neuron precursor cells immediately after termination of division. Also disclosed is a method that the cellular expression of 65B13 can be used as an index to efficiently isolate and select dopamine-producing neuron precursor cells that are suitable in terms of their safety, survival rate, and network formation ability, for transplant therapy of neurodegenerative diseases such as Parkinson's disease. <P>COPYRIGHT: (C)2007,JPO&INPIT |
申请公布号 |
JP2007050003(A) |
申请公布日期 |
2007.03.01 |
申请号 |
JP20060277440 |
申请日期 |
2006.10.11 |
申请人 |
EISAI R & D MANAGEMENT CO LTD |
发明人 |
NAKAGAWA YASUKO;ONO YUICHI;SAKAMOTO YOSHIMASA;MIZUHARA HIDEMICHI;NAKATANI TOMOYA;TAKAI YOSHIMI |
分类号 |
C12N15/09;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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