Methods of treating concomitant constipation in a cancer treatment regimen including imexon

摘要

Methods of treating imexon-induced constipation in patients in conjunction with their participation in a cancer treatment regimen are disclosed herein. Embodiments of the invention include the treatment of imexon-induced constipation arising from the administration of imexon alone or in combination with other chemotherapeutic agents. Also disclosed are pharmaceutical compositions and pharmaceutical kits comprising a therapeutically effective amount of imexon and an amount of a laxative effective in treating imexon-induced constipation. Embodiments of the present invention include prophylactic anticonstipation regimens comprising one or more laxatives that may be prescribed and/or administered prior to or during the course of treatment of the patient with imexon.