| 摘要 |
The present invention relates, in general, to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a polyvalent HIV vaccine, and to methods of using same. The invention further relates to methods that use a genetic algorithm to create sets of polyvalent antigens suitable for use, for example, in vaccination strategies. |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;BETH ISRAEL DEACONNESS MEDICAL CENTER;DUKE UNIVERSITY;THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION;KORBER, BETTE, T.;PERKINS, SIMON;BHATTACHARYA, TANMOY;FISCHER, WILLIAM, M.;THEILER, JAMES;LETVIN, NORMAN;HAYNES, BARTON, F.;HAHN, BEATRICE, H.;YUSIM, KARINA;KUIKEN, CARLA |
发明人 |
KORBER, BETTE, T.;PERKINS, SIMON;BHATTACHARYA, TANMOY;FISCHER, WILLIAM, M.;THEILER, JAMES;LETVIN, NORMAN;HAYNES, BARTON, F.;HAHN, BEATRICE, H.;YUSIM, KARINA;KUIKEN, CARLA |
