摘要 |
<P>PROBLEM TO BE SOLVED: To provide a microorganism whose target protein or polypeptide productivity is improved. <P>SOLUTION: This recombinant microorganism is obtained by transducing a gene encoding a target protein or polypeptide into a microorganism obtained by transducing the transcription start control region functioning in a microorganism or the transcription start control region and a ribosome-bound site into an upstream on the genome of Bacillus subtilis prs A gene or a gene corresponding to the gene, or by transducing a gene fragment connected to the upstream of Bacillus subtilis prs A gene or a gene corresponding to the gene, with the transcription start control region functioning in a microorganism or the transcription start control region and a ribosome-bound site and deleting or inactivating a spore-related gene or flagellum-related gene or one or more of genes corresponding to these genes. <P>COPYRIGHT: (C)2007,JPO&INPIT |