THERAPEUTICALLY ACTIVE a-MSH ANALOGUES

摘要

The invention describes peptide analogues of a-melanocyte-stimulating hormone (a-MSH), which posses an increased efficay compared to the native a-MSH peptide. The a-MSH analogues exhibit increased anti-inflammatory effects and increased capability to prevent ischemic conditions compared to a-MSH. The invention further discloses use of the peptides for the manufacture of pharmaceutical compositions for the treatment or prophylaxis of a condition in the tissue of one or more organs of a mammal, and moreover pharmaceutical compositions.