Crystal modification B of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8- diazabicyclo-[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3- quinoline carboxylic acid, methods for producing the same, and its use in pharmaceutical preparations

摘要

The invention provides a defined crystal modification B of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-[4.3.0]nonan-8- yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid of formula (I), method for producing the same, and its use in antibacterial pharmaceutical preparations. The crystal modification can be distinguished from other crystal modifications of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo- [4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid of formula (I) by its characteristic X-ray powder diffractogram and its differential thermal diagram.