发明名称 iRNA AGENTS TARGETING VEGF
摘要 The features of the present invention relate to compounds, compositions and methods useful for modulating the expression of vascular endothelial growth factor (VEGF), such as by the mechanism of RNA interference (RNAi). The compounds and compositions include iRNA agents that can be unmodified or chemically-modified.
申请公布号 WO2005089224(A3) 申请公布日期 2007.03.01
申请号 WO2005US08182 申请日期 2005.03.11
申请人 ALNYLAM PHARMACEUTICALS, INC.;DE FOUGEROLLES, ANTONIN;FRANK-KAMENETSKY, MARIA;MANOHARAN, MUTHIAH;RAJEEV, KALLANTHOTTAHIL, G.;HADWIGER, PHILLIPP 发明人 DE FOUGEROLLES, ANTONIN;FRANK-KAMENETSKY, MARIA;MANOHARAN, MUTHIAH;RAJEEV, KALLANTHOTTAHIL, G.;HADWIGER, PHILLIPP
分类号 C07H21/04;A61K9/00;A61K31/7088;A61K47/02;A61K47/10;A61K47/12;A61K47/48;A61K48/00;C12N15/113 主分类号 C07H21/04
代理机构 代理人
主权项
地址