Diaminopyrimidines as P2X3 and P2X2/3 modulators

摘要

Compounds and methods for treating diseases mediated by a P2X₃ and/or a P2X_2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): wherein D, X, R¹, R², R³, R⁴, R⁵, R⁶, R⁷ and R⁸ are as defined herein.