发明名称 |
ANTICANCER AND ANTIPROTOZOAL DIHYDROARTEMISINENE AND DIHYDROARTEMISITENE DIMERS WITH DESIRABLE CHEMICAL FUNCTIONALITIES |
摘要 |
This invention comprises compositions containing dihydroartemisinin- and dihydroartemisitene- dimers with activity as anticancer or anticancer metastasis agents and anti-protozal, including anti-malarial and anti-leishmanial properties. This invention also describes methods of preparation of these compositions and methods of use of such compositions for the treatment of cancer or prevention of cancer metastasis, and protozoal infections, including malaria, or leishmaniasis. The compounds of this invention represent a potential new class of anti-tumor or anti-metastasis agents, one that has shown promising activity against solid tumors.
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申请公布号 |
WO2006002105(A8) |
申请公布日期 |
2007.03.01 |
申请号 |
WO2005US21826 |
申请日期 |
2005.06.21 |
申请人 |
UNIVERSITY OF MISSISSIPPI;ELSOHLY, MAHMOUD, A.;GUL, WASEEM |
发明人 |
ELSOHLY, MAHMOUD, A.;GUL, WASEEM |
分类号 |
A61K31/357;C07D495/18 |
主分类号 |
A61K31/357 |
代理机构 |
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代理人 |
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地址 |
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