SEMI-SYNTHESIS OF TAXANE DERIVATIVES USING METAL ALKOXIDES AND BETA-LACTAMS.
摘要
<p>A PROCESS FOR PREPARING A TAXANE DERIVATIVE BY PROVIDING A METAL ALKOXIDE HAVING THE BI-, TRI- OR TETRACYCLIC TAXANE NUCLEUS, REACTING THE METAL ALKOXIDE WITH AΒ—LACTAM TO FORM AN INTERMEDIATE, AND CONVERTING THE INTERMEDIATE TO A TAXOL.</p>
