2,3-BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENT

摘要

The invention relates to 2,3-benzodiazepine derivatives of formula I and to pharmaceutical compositions comprising the same as active ingredient. The novel compounds have antispasmodic, muscle relaxing and neuroprotective activities. In formula I, X represents a hydrogen atom, a chlorine atom or a methoxy group; Y stands for a hydrogen atom or a halo atom; Z means a methyl group or a chlorine atom; R is a C1-4 alkyl group or a group of the formula -NR1R2, wherein R1 and R2 represent, independently, a hydrogen atom, a C1-4 alkyl group, a C1-4 alkoxy group or a C3-6 cycloalkyl group.