| 发明名称 |
SELECTIVE KILLING OF CANCER CELLS BY INDUCTION OF ACETYLTRANSFERASE VIA TNF-ALPHA AND IL-6 |
| 摘要 |
<p>This invention relates to up-regulation of the acetyltransferase MCM3AP by the administration of the cytokines TNFalpha and IL-6 and, optionally a deacetylase inhibitor. This up-regulation is shown herein to be selectively lethal to cancer cells and has applications in the treatment of cancer.</p> |
| 申请公布号 |
EP1755649(A1) |
申请公布日期 |
2007.02.28 |
| 申请号 |
EP20050732631 |
申请日期 |
2005.04.13 |
| 申请人 |
MEDICAL RESEARCH COUNCIL |
发明人 |
DRAYTON, SARAH;TAKEI, YOSHINORI |
| 分类号 |
A61K38/19;A61K31/165;A61K38/20;A61K45/06;A61P35/00;G01N33/50 |
主分类号 |
A61K38/19 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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