DERIVATIVES OF ARYL(OR HETEROARYL)AZOLYLCARBINOL FOR TREATMENT OF RESPIRATORY DISEASE

摘要

FIELD: organic chemistry, medicine. ^ SUBSTANCE: invention proposes using aryl(or heteroaryl)azolylcarbinol of the general formula (I) wherein Ar means possibly substituted phenyl or thienyl; R means hydrogen atom or alkyl; R2 means dialkylaminoalkyl or azaheterocyclylalkyl; Het means unsubstituted azol of substituted with one or two substitutes, and their salts. Proposed derivatives can be used as an agent for treatment of chronic obstructive pulmonary diseases (cough, bronchitis, allergic rhinitis and asthma). Proposed compound depresses cough being without sedative effect. ^ EFFECT: valuable medicinal properties of compounds. ^ 4 cl, 1 tbl, 3 ex