发明名称 |
C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases |
摘要 |
This invention is directed to novel oxamyl dipeptide ICE/ced-3 family inhibitor compounds. The invention is also directed to pharmaceutical compositions containing these compounds, as well as to the use of such compositions in the treatment of patients suffering inflammatory, autoimmune and neurodegenerative diseases, for the prevention of ischemic injury, and for the preservation of organs that are to undergo a transplantation procedure.
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申请公布号 |
US7183260(B2) |
申请公布日期 |
2007.02.27 |
申请号 |
US20040926800 |
申请日期 |
2004.08.25 |
申请人 |
IDUN PHARMACEUTICALS, INC. |
发明人 |
KARANEWSKY DONALD S;TERNANSKY ROBERT J;LINTON STEVEN D;DINH THANG |
分类号 |
C07D307/33;C07K5/06;A61K31/341;A61K38/00;A61K38/05;A61P1/04;A61P1/16;A61P3/10;A61P5/14;A61P7/00;A61P7/04;A61P7/06;A61P9/10;A61P11/00;A61P13/12;A61P17/02;A61P17/12;A61P19/02;A61P21/04;A61P25/00;A61P25/16;A61P25/28;A61P29/00;A61P31/04;A61P31/12;A61P31/14;A61P31/16;A61P31/20;A61P37/00;A61P37/02;A61P43/00;C07C237/12;C07C237/22;C07C317/50;C07D295/135;C07D295/185;C07F9/32;C07K5/023 |
主分类号 |
C07D307/33 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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