发明名称 |
Methods of increasing distribution of nucleic acids |
摘要 |
This invention provides a method of increasing the volume of distribution of a nucleic acid encoding a therapeutic agent in a tissue in a subject during localized delivery, comprising administering to the tissue in the subject a nucleic acid encoding a therapeutic agent and a facilitating agent, whereby the inclusion of the facilitating agent increases the volume of distribution of the nucleic acid encoding a therapeutic agent in the tissue.
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申请公布号 |
US7182944(B2) |
申请公布日期 |
2007.02.27 |
申请号 |
US20020132681 |
申请日期 |
2002.04.25 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
BANKIEWICZ KRYS |
分类号 |
A01N63/00;A61K48/00;C12N15/864 |
主分类号 |
A01N63/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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