| 摘要 |
#CMT# #/CMT# Paraphenylenediamine compound (I) and their solvates or salts of acids, are new. #CMT# : #/CMT# Paraphenylenediamine compound of formula (I) and their solvates or salts of acids, are new.R1, R2 = 1-6C alkyl (optionally substituted with 1-6C alkyl, OH, NH2, alkyl(1-6C)amino or dialkyl(1-6C)amino or cyclic group like 1-pyrrolidinyl, 1-cyclohexylaminyl, 1-piperazinyl, 1-diazepanyl, 1-morpholinyl or 1-imidazoyl (all optionally with alkyl, OH or NH2)), 1-6C alkoxy, 1-6C monohydroxyalkoxy or 1-6C polyhydroxyalkoxy, carboxylic group or amide group. Provided that (I) is excluding from 2,6-dimethyl-benzene-1,4-diamine, 2,6-diethyl-benzene-1,4-diamine, 2,6-diisopropyl-benzene-1,4-diamine, 2,6-di-tertiary butyl-benzene-1,4-diamine and 2,6-dimethoxy-benzene-1,4-diamine. Independent claims are included for: (1) the preparation of (I); (2) a 4-nitro-phenylamine compounds of formulae (II), (III) and (IV); (3) a composition in a medium for the oxidation dyeing of keratinous fibers comprising (I); (4) a process of coloring the keratinous fibers, particularly human keratinous fibers e.g. hair comprising applying the composition in the presence of air or an oxidizing agent or optionally in the presence of oxidation catalysts; and (5) a device with compartments or dyeing kit with compartments, where first compartment contains the composition and second compartment contains an oxidizing composition. R2-a : 1-4C alkyl (optionally substituted with 1-6C alkoxy, OH, NH2, alkyl(1-6C)amino, dialkyl(1-6C)amino or cyclic ring like 1-pyrrolidinyl, 1-cyclohexylaminyl, 1-piperazinyl, 1-diazepanyl, 1-morpholinyl or 1-imidazoyl (all optionally substituted with alkyl, OH or NH2)), 1-6C alkoxy, 1-6C monohydroxyalkoxy or 1-6C polyhydroxyalkoxy; and R3H or sulfonyl. Provided that: (II) is excluding from 2,6-diethyl-4-nitro-phenylamine, 2-amino-3-ethyl-5-nitro-benzoic acid, 2,6-diisopropyl-4-nitro-phenylamine, 2,6-dimethyl-4-nitro-phenylamine, 2-amino-3-methoxy-5-nitro-benzoic acid, 2-tert-butyl-6-methyl-4-nitro-phenylamine, 2,6-di-tert-butyl-4-nitro-phenylamine, 2,6-dimethoxy-4-nitro-phenylamine, 2-methoxy-6-methyl-4-nitro-phenylamine and 2-amino-3-methyl-5-nitro-benzoic acid; (III) is excluding from 2,6-dimethyl-4-phenylazo-phenylamine, 2,6-diisopropyl-4-phenylazo-phenylamine, 4-(4-amino-3-sec-butyl-5-ethyl-phenylazo)-benzenesulfonic acid, 4-(4-amino-3-tert-butyl-5-methyl-phenylazo)-benzenesulfonic acid and 4-(4-amino-3-isopropyl-5-methyl-phenylazo)-benzenesulfonic acid; and (III) is excluding from 2-methyl-4-nitro-6-pent-1-ynyl-phenylamine. #CMT#[Image]#/CMT# #CMT#[Image]#/CMT# #CMT#USE : #/CMT# (I) is useful in the dyeing composition for the keratinous fibers, particularly human keratinous fibers e.g. hair (claimed). (I) is useful to dye human grey hair. #CMT#ADVANTAGE : #/CMT# (I) is devoid of toxicity; provides required color intensity; and good against external aggressions e.g. light, bad weather, washing, perspiration and frictions. #CMT#INORGANIC CHEMISTRY : #/CMT# Preferred Components: The oxidizing agent is hydrogen peroxide, urea peroxide, alkaline metal bromates, persalts like perborates or persulfates. Preferred Process: The coloring is revealed with the contact of oxygen in air and an acid, neutral or an alkaline pH using an oxidizing agent, which is added at the time of application or present in the composition applied simultaneously or sequentially in a separate way. #CMT#ORGANIC CHEMISTRY : #/CMT# Preparation (Claimed): Preparation of (I) comprises reducing 4-nitro-phenylamine compound of formula (II), (III) or (IV). Preferred Composition: The composition comprises (I) at 0.001-10 wt.%, preferably 0.1-3 wt.%. The composition has a pH of 3-13. The composition further comprises: an additional oxidation base; and a coupler and/or a direct dye. Preferred Components: The medium is water or a mixture of water and an organic solvent like lower 1-4C alkanols, polyols, polyol ethers and/or aromatic alcohols. The base is para-phenylenediamine that is different from (I), bisphenylalkylenediamines, para-aminophenols, ortho-aminophenols, heterocyclic bases or their additive salts with an acid. The base is present at 0.0005-12 wt.%. The coupler is meta-phenylenediamine, meta-aminophenols, meta-diphenols, mono or polyhydroxyls derivatives of naphthalene or heterocyclic couplers or their additive salts of an acid. The coupler is present at 0.0001-10 wt.%. The acid forming salts are hydrochloric acid, hydrobromic acid, sulfuric acid, acetic acid, lactic acid, tartaric acid, citric acid, methanesulfonic acid, para-toluenesulfonic acid, benzenesulfonic acid, phosphoric acid or succinic acid. #CMT#DEFINITIONS : #/CMT# Preferred Definitions: R1, R2CH3, C2H5, n-propyl, iso-propyl, sec-butyl, iso-butyl, tert-butyl, (2,2'dimethyl)butyl, methoxybutyl, aminomethyl, (3-dimethylamino)propyl, imidazolo-n-propyl, pyrrolidinoethyl, methoxy, hydroxymethyl, a-hydroxyethyl, 3-hydroxyethyl, p-hydroxy-iso-propyl, carboxylic group or amido group. #CMT#SPECIFIC COMPOUNDS : #/CMT# 26 Compounds (I) are specifically claimed e.g. 2-isopropyl-6-methyl-benzene-1,4-diamine of formula (Ia). #CMT#EXAMPLE : #/CMT# No suitable example given. |
