发明名称 Nozel azalide and azalactam derivatives and method for producing the same
摘要 A compound represented by the following general formula (1) or a pharmaceutically acceptable salt thereof, which is useful for a prophylactic and/or therapeutic treatment of a microbial infectious disease. [R<SUB>1 </SUB>is hydrogen atom, or a linear C1-6 alkylcarbonyl group; R<SUB>2 </SUB>is hydrogen atom, or a C1-6 alkylcarbonyl group; R<SUB>3 </SUB>is hydrogen atom, a C1-6 alkyl group, a C1-6 alkylcarbonyl group, a C1-6 alkenyl group, a C2-6 alkenylcarbonyl group, a C2-6 alkynyl group, or an Ar-B- group (Ar represents an aryl group, or a heterocyclic group, and B is a C1-6 alkyl group, a C1-6 alkylcarbonyl group, a C2-6 alkenyl group, a C2-6 alkenylcarbonyl group, or a C2-6 alkynyl group); R<SUB>5</SUB>, R<SUB>6</SUB>, R<SUB>7</SUB>, and R<SUB>8 </SUB>represent hydrogen atom, a C1-6 alkyl group, a C2-6 alkenyl group, a C2-6 alkynyl group, or an Ar-B'- group (B' is a C1-6 alkyl group, a C2-6 alkenyl group, or a C2-6 alkynyl group); X is oxygen atom, or an -NR<SUB>4</SUB>- group (R<SUB>4 </SUB>is hydrogen atom, a C1-6 alkyl group, or a C1-6 alkyl group which may be substituted with an Ar group); and R<SUB>4'</SUB> is hydrogen atom, or a group represented by the aforementioned formula (a) (R<SUB>3''</SUB> and R<SUB>4''</SUB> represent hydrogen atom, or a linear or branched C1-6 alkylcarbonyl group)]
申请公布号 US2007042974(A1) 申请公布日期 2007.02.22
申请号 US20040569063 申请日期 2004.08.20
申请人 MIURA TOMOAKI;KANEMOTO KENICHI;NATSUME SATOMI;OHKURA NAOTO;FUJIHIRA YUMIKO;WATANABE TAKASHI;FUSHIMI HIDEKI;ATSUMI KUNIO;AJITO KEIICHI 发明人 MIURA TOMOAKI;KANEMOTO KENICHI;NATSUME SATOMI;OHKURA NAOTO;FUJIHIRA YUMIKO;WATANABE TAKASHI;FUSHIMI HIDEKI;ATSUMI KUNIO;AJITO KEIICHI
分类号 A61K31/7052;A61P31/04;C07H15/04;C07H17/00;C07H17/08 主分类号 A61K31/7052
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