BICYCLIC PIPERAZINES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS

摘要

The invention relates to compounds of formula I or pharmaceutically acceptab le salts or solvates thereof: where Ar1, A Hy, R1, m and n are as defined in th e description. The invention also includes pharmaceutical compositions and use s of, and processes of making the compounds, as well as methods of medical treatment of mGluR5-mediated disorders.