| 发明名称 |
NOVEL GENE UNDERLYING ATHEROSCLEROSIS LOCUS I |
| 摘要 |
This invention provides an isolated nucleic acid encoding Adamtsl-1 protein and related compositions. This invention further provides a method of inhibiting expression of Adamtsl-1 in a cell. This invention further provides a method for inhibiting the onset of atherosclerosis in a subject and a method of treating atherosclerosis in a subject. This invention further provides transgenic animals. Finally, this invention provides for a method of screening for possible candidate agents for treating a human afflicted with atherosclerosis.
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| 申请公布号 |
WO2006084007(A3) |
申请公布日期 |
2007.02.22 |
| 申请号 |
WO2006US03645 |
申请日期 |
2006.02.01 |
| 申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;TALL, ALAN R.;WELCH, CARRIE;SEIDELMANN, SARA BRETSCHGER |
发明人 |
TALL, ALAN R.;WELCH, CARRIE;SEIDELMANN, SARA BRETSCHGER |
| 分类号 |
A61K39/395;A01K67/00;A01K67/027;A01K67/033;C07H21/02;C07H21/04;C07K1/00;C07K14/00;C07K17/00;C12N5/00;C12N5/02;C12N15/00;C12N15/09;C12N15/63;C12N15/70;C12N15/74;G01N33/00 |
主分类号 |
A61K39/395 |
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