| 摘要 |
The invention provides novel kinase inhibitors that are useful as therapeutic agents for example in the treatment malignancies where the compounds have the general formula I (I) wherein A, X, Y, Z, Ra, Rb, Rc, R<SUB>1</SUB> , R<SUB>2</SUB>, R<SUB>3</SUB> and m are defined herein. |
| 申请人 |
GENENTECH, INC.;HOFFMAN-LA ROCHE, INC.;F. HOFFMAN-LA ROCHE, AG;ZHOU, AIHE;RAWSON, THOMAS, E.;SAFINA, BRIAN;DOTSON, JENNAFER;ALIAGAS-MARTIN, IGNACIO;HALLADAY, JASON;LIANG, JUN;RUETH, MATTHIAS;ZHU, BING-YAN;BROOKFIELD, FREDERICK;PRIME, MICHAEL;ZHANG, BIRONG;LI, JUN, M. |
发明人 |
RAWSON, THOMAS, E.;SAFINA, BRIAN;DOTSON, JENNAFER;ALIAGAS-MARTIN, IGNACIO;HALLADAY, JASON;LIANG, JUN;RUETH, MATTHIAS;ZHU, BING-YAN;BROOKFIELD, FREDERICK;PRIME, MICHAEL;ZHANG, BIRONG;LI, JUN, M. |
