COMPOSITIONS FOR INDUCING AN IMMUNE RESPONSE AGAINST TUMOR ANTIGENS

摘要

Priming and boosting compositions and methods for inducing an immune response, e.g. a CD8+ T cell response, to an antigen e.g. a tumour antigen, for example a melanoma antigen. Methods of treating metastasis of melanoma in mammals. DNA plasmids and/or poxvirus, e.g. modified vaccinia virus Ankara, as priming and/or boosting compositions for inducing immune responses to antigen epitopes.