PHROPHYLACTIC AND/OR THERAPEUTIC METHOD FOR TREATMENT OF AUTOIMMUNE DISEASE

摘要

The present invention provides therapeutic and/or prophylactic method comprising administering to a subject an amount of a composition sufficient to reduce or deplete antibody producing cells and/or prevent expansion of said cells in a tissue or organ of a subject suffering from T cell mediated autoimmune disease e.g., type 1 diabetes, or at risk of suffering from said disease, preferably wherein the composition is administered immediately prior to or concomitant with an autoimmune response. The present invention also provides the use of said composition in the manufacture of a medicament for the treatment and/or prevention of T cell mediated autoimmune disease. The present invention also provides said composition for use in the treatment and/or prevention of T cell mediated autoimmune disease.