发明名称 |
COMPOUNDS AND COMPOSITIONS AS HEDGEHOG PATHWAY MODULATORS |
摘要 |
The invention provides a method for modulating the activity of the hedgehog signaling pathway. In particular, the invention provides a method for inhibiting aberrant growth states resulting from phenotypes such as Ptc loss-of-function, hedgehog gain-of-function, smoothened gain-of-function or Gli gain-of-function, comprising contacting a cell with a sufficient amount of a compound of Formula I.
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申请公布号 |
WO2006050351(A3) |
申请公布日期 |
2007.02.22 |
申请号 |
WO2005US39442 |
申请日期 |
2005.10.28 |
申请人 |
IRM LLC;WU, XU;DING, SHENG;SCHULTZ, PETER, G. |
发明人 |
WU, XU;DING, SHENG;SCHULTZ, PETER, G. |
分类号 |
A61K31/542;A61K31/435;A61K31/437 |
主分类号 |
A61K31/542 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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