Sustained delivery pharmaceutical compositions comprising a solid ionic complex of a pharmaceutically active compound and an ionic macromolecule are provided by the present invention. The pharmaceutical compositions of the invention allow for loading of high concentrations of pharmaceutically active compounds and for delivery of a pharmaceutically active compound for prolonged periods of time, e.g., one month, after administration. Methods for preparing these pharmaceutical compositions, as well as methods of using them to treat a subject are also provided.
申请公布号
WO2007022255(A2)
申请公布日期
2007.02.22
申请号
WO2006US31968
申请日期
2006.08.15
申请人
PRAECIS PHARMACEUTICALS, INC.;BARKER, NICHOLAS;WOLFE, JANET, L.