INFLUENZA RECOMBINANT SUBUNIT VACCINE

摘要

The invention provides influenza proteins, including subunit proteins and immunogenic compositions that can be utilized, with or without adjuvants, a s vaccines to protect against influenza infection in animal models and human s. The recombinant proteins are expressed from transformed insect cells that contain integrated copies of the appropriate expression cassettes in their genome. The invention uses a Drosophila melanogaster expression system to pr ovide high yields of recombinant subunit proteins with native-like conformat ion.