发明名称 Processes for preparing alkyl 3-(4-tetrahydropyranyl)-3-oxopropanoate compound and 4-acyltetrahydropyrane
摘要 The present invention is to provide a process for preparing an alkyl 3-(4-tetrahydropyranyl)-3-oxopropanoate compound represented by the formula (1): wherein R<SUP>1 </SUP>and R<SUP>2 </SUP>may be the same or different from each other, and represent a group which does not participate in the reaction, and R<SUP>1 </SUP>and R<SUP>2 </SUP>may be bonded to form a ring, and the ring may contain a hetero atom(s), and R<SUP>3 </SUP>represents a hydrocarbon group, which comprises reacting 4-acyltetrahydropyran represented by the formula (2): wherein R<SUP>1 </SUP>and R<SUP>2 </SUP>have the same meanings as defined above, and a carbonic acid diester represented by the formula (3): wherein R<SUP>3 </SUP>has the same meanings as defined above, and two R<SUP>3</SUP>s may be bonded to each other to form a ring, in the presence of a base, and a process for preparing 4-acyltetrahydropyran.
申请公布号 US2007043107(A1) 申请公布日期 2007.02.22
申请号 US20040583473 申请日期 2004.12.17
申请人 UBE INDUSTRIES, LTD. 发明人 NISHINO SHIGEYOSHI;HIROTSU KENJI;SHIMA HIDETAKA;IWAMOTO KEIJI;HARADA TAKASHI
分类号 A61K31/35;C07B61/00;C07D309/06 主分类号 A61K31/35
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