COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF HYPERURICEMIA RELATED HEALTH CONSEQUENCES
摘要
<p>Disclosed herein are methods of delaying the onset or treating diabetes that comprises administering a uric acid lowering agent. The inventors have made the remarkable discovery that elevated uric acid levels are not a corollary to insulin resistance, but rather a primary mediator of insulin resistance. Specifically exemplified are methods that involve administering to a patient susceptible to development of diabetes a composition comprising a uric acid lowering agent in a regimen that maintains serum uric acid levels below at least 5.5 mg/dl, or below at least 5.2 mg/dl.</p>
申请公布号
WO2007018687(A1)
申请公布日期
2007.02.15
申请号
WO2006US20998
申请日期
2006.05.31
申请人
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.;JOHNSON, RICHARD, J.;NAKAGAWA, TAKAHIKO