| 摘要 |
An inhibitor contains naphthyridine dimer, a naphthyridine-azaquinolone hybrid, a trinaphthyridine-azaquinolone hybrid, or a trinaphthyridine-azaquinolone hybrid derivative. In order to inhibit binding of 100 nM of RRE to 100 nM of Rev protein, for example, an inhibitor containing naphthyridine dimer is used at a molarity of 1.2 muM to 12 muM, an inhibitor containing the naphthyridine-azaquinolone hybrid is used at a molarity of 2 muM to 20 muM, or an inhibitor containing the trinaphthyridine-azaquinolone hybrid derivative is used at a molarity of 200 nM to 2 muM. This makes it possible to effectively inhibit binding of RRE to Rev protein.
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