Substance which exhibits antiviral and antibacterial activity and is based on derivatives of 2,8-dithioxo-1h-pyrano[2,3d 6,5-d']dipyrimidyne and 10-aza-analogue thereof

摘要

The invention relates to organic chemistry and medicine, more specifically to synthetic pyrimidine derivatives, i.e. 2,8-dithioxo-1H-pyrano[2,3d,6,5-d']dipyrimidyne and 10-aza-analogue thereof and to the complexes and salts thereof which exhibit antiviral and antimicrobial activity. Said invention can be used for medicine and veterinary science for treating viral diseases, bacteria-induced diseases and for cosmetology in the form of an additive for preventing and treating infections. The aim of said invention is to develop a novel more efficient substance exhibiting antiviral and antimicrobial activity. The inventive substance which exhibits antiviral and antimicrobial activity is based on derivatives of 2,8-dithioxo-1H-pyrano[2,3d,6,5-d']dipyrimidyne and 10-aza-analogue thereof and characterised in that it comprises the derivative of said group of general formula A1, M, wherein X is selected from a group O, NH, N-Alkyl; R1 is selected from a group H, Oh, Cl, O-Alkyl, NH₂, NH-Alkyl, NH-Ar, N(Alkyl)₂, SH, S-Alkyl, S-Ar, S-Hetaryl; R₂ is selected from a group C₆H₅, Aryl, R3 is selected from a group H, Cl, O-Alkyl, NH₂, NH-Alkyl, NH-Ar, S-Heratyl, M is absent or selected from a group of Na, K, Li, ammonium cation or another pharmacologically acceptable cation; or said complex of pharmacologically acceptable cation with the anion of one of derivatives Al (above-mentioned variants R₁-R₃).