摘要 |
The present invention relates to compounds of the general formula (III) or pharmaceutically acceptable salts thereof with an acid or a base, or pharmaceutically acceptable prodrugs or a stereoisomer thereof, Formula (III ) wherein R3 is H, -C(O)NRaRb, halogen, alkyl, haloalkyl, aryl, heteroaryl, OH , SH, NR4~ OR5~ , NH2, amine, alkylamine, alkoxy, cycloalkyl, heterocyclo- alkyl,hydroxyalkyl, or haloalkyloxy; R4 is H, halogen, alkyl, -C(NR7)NR7~R8, - (CH2)paryl, -(CH2)PNR7R8, -C(O)NR7R8, -N=CR7R8, -NR7C(O)R8, cycloalkyl, heterocycloalkyl, haloalkyl, hydroxyalkyl, hydroxyalkylamino, alkylamino, heteroaryl, or aryl; R5 is halogen, alkyl, -C(NR7)NR7~R8, -(CH2)paryl, - (CH2)PNR7R8, -C(O)NR7R8, -N=CR7R8, -NR7C(O)R8, cycloalkyl, heterocycloalkyl, haloalkyl, hydroxyalkyl, hydroxyalkylamino, alkylamino, heteroaryl, or aryl.
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