| 摘要 |
Scaffolds for tissue engineering, and methods and systems for manufacturing the same. The starting material used to manufacture the scaffolds may include a needled non-woven sheet, or a batt of fibers. In either case, the starting material includes a bioabsorbable polymer, such as polyglycolic acid or poly-L-lactide. This allows the scaffold to dissolve when exposed to water (e.g., when placed in the body). The starting material is needled into a three dimensional shape that is substantially seamless and then set with heat and pressure to provide substantially uniform thickness and density. This affords an improved substrate on which to place cells that will form the tissue.
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