发明名称 |
Fluorogenic enzyme substrates and methods of preparation |
摘要 |
This invention relates to hydrolase fluorogenic substrates with improved cell permeability, methods for the preparation thereof, and methods of measuring activities of hydrolases, particularly in cell-based assays. The substrates easily diffuse into the cells, where they are enzymatically processed to yield photostable fluorescent products, and are particularly fitted for visualising enzyme-derived activities in cell-based assays.
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申请公布号 |
US2007037234(A1) |
申请公布日期 |
2007.02.15 |
申请号 |
US20030540057 |
申请日期 |
2003.12.26 |
申请人 |
GOEMAN JAN L;VAN ACKER KOENRAAD L A;VAN DER EYCKEN JOHAN T A;DIERYNCK INGE |
发明人 |
GOEMAN JAN L.;VAN ACKER KOENRAAD L.A.;VAN DER EYCKEN JOHAN T.A.;DIERYNCK INGE |
分类号 |
C12Q1/66;C07D239/72;C07D239/91;C07F9/6512;C07H15/00;C07H15/26 |
主分类号 |
C12Q1/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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