发明名称 FUSED BICYCLOHETEROCYCLE SUBSTITUTED QUINUCLIDINE DERIVATIVES
摘要 Compounds of formula (I) wherein n is 0, 1, or 2; A is N or N+-O-; X is O, S , - NH-, and -N-alkyl-; Ar1 is a 6-membered aromatic ring; and Ar2 is a fused bicycloheterocycle. The compounds are useful in treating conditions or disorders prevented by or ameliorated by .alpha.7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) an d methods for using such compounds and compositions.
申请公布号 CA2611674(A1) 申请公布日期 2007.02.15
申请号 CA20062611674 申请日期 2006.06.14
申请人 ABBOTT LABORATORIES 发明人 BUNNELLE, WILLIAM H.;PAN, LIPING;NERSESIAN, DIANA L.;SCHRIMPF, MICHAEL R.;LI, TAO;MORTELL, KATHLEEN H.;JI, JIANGUO
分类号 C07D453/02;A61K31/439;A61P25/28 主分类号 C07D453/02
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