发明名称 |
FUSED BICYCLOHETEROCYCLE SUBSTITUTED QUINUCLIDINE DERIVATIVES |
摘要 |
Compounds of formula (I) wherein n is 0, 1, or 2; A is N or N+-O-; X is O, S , - NH-, and -N-alkyl-; Ar1 is a 6-membered aromatic ring; and Ar2 is a fused bicycloheterocycle. The compounds are useful in treating conditions or disorders prevented by or ameliorated by .alpha.7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) an d methods for using such compounds and compositions.
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申请公布号 |
CA2611674(A1) |
申请公布日期 |
2007.02.15 |
申请号 |
CA20062611674 |
申请日期 |
2006.06.14 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
BUNNELLE, WILLIAM H.;PAN, LIPING;NERSESIAN, DIANA L.;SCHRIMPF, MICHAEL R.;LI, TAO;MORTELL, KATHLEEN H.;JI, JIANGUO |
分类号 |
C07D453/02;A61K31/439;A61P25/28 |
主分类号 |
C07D453/02 |
代理机构 |
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地址 |
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