| 发明名称 |
DUAL SMALL MOLECULE INHIBITORS OF CANCER AND ANGIOGENESIS |
| 摘要 |
The present invention provides analogs and derivatives of thalidomide which inhibit cancer and angiogenesis. The present invention further provides compounds which disrupt microtubule polymerization. The present further provides methods of treating cancers comprising mutant p53. |
| 申请公布号 |
EP1750706(A1) |
申请公布日期 |
2007.02.14 |
| 申请号 |
EP20050756099 |
申请日期 |
2005.06.01 |
| 申请人 |
UNIVERSITY OF VIRGINIA PATENT FOUNDATION |
发明人 |
BROWN, MILTON, L. |
| 分类号 |
C07D217/24;A61K31/47;A61K31/495;A61K31/517;A61K31/5513;A61K49/00;A61P35/00;C07D221/12;C07D221/16;C07D223/16;C07D237/30;C07D239/91;C07D243/14;C07D245/04;C07D245/06;C07D401/12;C07D405/04;C07D409/04;C07D471/04;C07D487/04;C07D491/04;C07D495/04 |
主分类号 |
C07D217/24 |
| 代理机构 |
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代理人 |
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