Process for preparation of optionally substituted trifluoromethyl phenacyl bromide

摘要

Preparation of trifluoromethylphenacyl bromide (I) comprises reacting trifluoromethylacetophenone compound (II) with at least one brominating agent in the absence of solvent or in the presence of hard water soluble or water-immiscible solvent; and crystallizing the obtained raw product of (I) at -78[deg]C to +15[deg]C in the presence of at least an organic solvent. Preparation of trifluoromethylphenacyl bromide compound of formula (I) comprises reacting trifluoromethylacetophenone compound of formula (II) with at least one brominating agent in the absence of solvent or in the presence of hard water soluble or water-immiscible solvent; and crystallizing the obtained raw product of (I) at -78[deg]C to +15[deg]C in the presence of at least an organic solvent. [Image].