Isolated polypeptides and compositions from the venom of P. transvaalicus and methods of use

摘要

The invention provides isolated polypeptides from the venom of the scorpion P. transvaalicus. The invention also provides novel scorpion antivenom compositions derived from such polypeptides, as well as methods for isolating the polypeptides and preparing scorpion antivenom compositions. The isolated polypeptides can be used to produce pharmaceutical compositions useful for treating diseases and conditions associated with ion channel function or kinin activity.