发明名称 |
EBV-infected stomach cancer cell line |
摘要 |
An EBV strain infecting epithelial cells and a stomach cancer cell line cancerated by EBV are established to clarify the mechanism of canceration of epithelial cells into stomach cancer by EBV and to develop a chemotherapeutic agent for stomach cancer cancerated by EBV. Further, a stomach cancer cell line stably producing EBV-related antigens is established to develop a diagnostic drug for stomach cancer cancerated by EBV. According to the present invention, GTC-4 cell line was established through culture of stomach cancer tissues. GTC-4 produced the EBV strain infecting epithelial cells and simultaneously produced EBV-related antigens stably in the supernatant.
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申请公布号 |
US7176020(B2) |
申请公布日期 |
2007.02.13 |
申请号 |
US20020320608 |
申请日期 |
2002.12.17 |
申请人 |
EISAI CO., LTD. |
发明人 |
TAJIMA MASAKO;TAKANASHI MASAKATSU;MIYAZAWA YUKIHISA;TAKESHIMA TOSHIO;OKINAGA KOTA |
分类号 |
C12N5/00;C12N15/09;A61K45/00;A61P35/00;C07K14/05;C12N5/02;C12N5/06;C12N5/08;C12N7/00;C12N7/01;C12P19/34;C12P21/02;G01N33/15;G01N33/50 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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