| 发明名称 |
Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents |
| 摘要 |
The present invention relates to novel compounds that can be used as antiinflammatory, immunomodulatory and antiproliferatory agents. In particular the invention refers to new compounds which inhibit dihydroorotate dehydrogenase (DHODH), a process for their manufacture, pharmaceutical compositions containing them and to their use for the treatment and prevention of diseases, in particular their use in diseases where there is an advantage in inhibiting dihydroorotate dehydrogenase (DHODH).
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| 申请公布号 |
US7176241(B2) |
申请公布日期 |
2007.02.13 |
| 申请号 |
US20020193526 |
申请日期 |
2002.07.09 |
| 申请人 |
4SC AG |
发明人 |
LEBAN JOHAN;KRAMER BERND;SAEB WAEL;GARCIA GABRIEL |
| 分类号 |
A61K31/165;A61K31/167;A61K31/192;A61K31/194;A61K31/195;A61K31/215;A61K31/277;A61K31/341;A61K31/381;A61K31/382;A61K31/44;A61K31/4406;A61P11/02;A61P11/06;A61P17/06;A61P19/02;A61P27/02;A61P29/00;A61P31/00;A61P31/12;A61P33/02;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07C61/06;C07C69/74;C07C233/58;C07C233/59;C07C233/60;C07C233/62;C07C251/12;C07C255/60;C07C317/40;C07C323/40;C07D213/56;C07D213/64;C07D307/30;C07D333/38;C07D333/58;C07D335/12 |
主分类号 |
A61K31/165 |
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