发明名称 |
Manufacture and purification of cyclosporin A |
摘要 |
The present invention provides an improved method for the manufacture of Cyclosporin A is disclosed. Cyclosporin A is produced by solid state fermentation of Fusarium solani in a bioreactor under optimal fermentation parameters. The product is extracted and further purified by treating with alum and subsequent chromatographic procedures to get pharmaceutical acceptable purity.
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申请公布号 |
US7176001(B1) |
申请公布日期 |
2007.02.13 |
申请号 |
US20030220226 |
申请日期 |
2003.10.23 |
申请人 |
BIOCON LIMITED |
发明人 |
KHEDKAR ANAND PRAKASH;SUBRAMANIYAM PAMPAPATHY;ANAND KONAYAKANAHALLI NANJUNDA SWAMY;RAMKRISHNA MELARKODE;TAMBE SHREEHAS PRADEEP;GANESH SAMBASIVAM;SIRCAR ANINDYA;SURYANARAYAN SHRIKUMAR |
分类号 |
C12P21/04;C12P21/02 |
主分类号 |
C12P21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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