发明名称 |
Short peptide carrier system for cellular delivery of agent |
摘要 |
A dipeptide or tripeptide carrier system for active agent delivery to cells has an N-terminus natural amino acid and an active agent covalently bonded to a side chain of one of the remaining amino acid bases. The system is amenable to formulation as an oral administrant. The active agent being a therapeutic, a fluorescent dye, or contrast agent where the active agent has a molecular weight of less than 500 atomic mass units. An optional linker is provided intermediate between the active agent and the linking side chain.
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申请公布号 |
US7176185(B2) |
申请公布日期 |
2007.02.13 |
申请号 |
US20040997036 |
申请日期 |
2004.11.24 |
申请人 |
TSRL, INC. |
发明人 |
HILFINGER JOHN;KISH PHILLIP |
分类号 |
C07K5/06;A61K9/14;C07K7/08;C12P21/04;C12Q1/00;G01N33/50 |
主分类号 |
C07K5/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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