INTERLEUKIN-1 AND TUMOR NECROSIS FACTOR-A MODULATORS; SYNTHESES OF SUCH MODULATORS AND METHODS OF USING SUCH MODULATORS

摘要

Compounds are disclosed that have the chemical structure of Formula (II), (IIA) and (IIB) and their prodrug esters and acid-addition salts, and that a re useful as Interleukin-1 and Tumor Necrosis Factor-a modulators, and thus are useful in the treatment of various diseases, wherein the R groups are define d in the claims.