发明名称 Hsp90 family protein inhibitors
摘要 The present invention provides Hsp90 family protein inhibitors comprising, as an active ingredient, a benzoyl compound represented by general formula (I): (wherein n represents an integer of 0 to 10; R<SUP>1 </SUP>represents substituted or unsubstituted lower alkoxy, substituted or unsubstituted lower alkoxycarbonyl, CONR<SUP>7</SUP>R<SUP>8 </SUP>or the like; R<SUP>2 </SUP>represents substituted or unsubstituted aryl, a substituted or unsubstituted aromatic heterocyclic group or the like; R<SUP>3 </SUP>and R<SUP>5</SUP>, which may be the same or different, each represent a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl or the like; and R<SUP>4 </SUP>and R<SUP>6</SUP>, which may be the same or different, each represent a hydrogen atom, halogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl or the like) or a prodrug thereof, or a pharmaceutically acceptable salt of said benzoyl compound or said prodrug.
申请公布号 US2007032532(A1) 申请公布日期 2007.02.08
申请号 US20050561415 申请日期 2005.12.19
申请人 KYOWA HAKKO KOGYO CO., LTD. 发明人 NARA SHINJI;NAKAGAWA HIROSHI;KANDA YUTAKA;NAKASHIMA TAKAYUKI;SOGA SHIRO;KAJITA JIRO;SAITO JUN-ICHI;SHIOTSU YUKIMASA;AKINAGA SHIRO
分类号 A61K31/4192;A61K31/12;A61K31/165;A61K31/195;A61K31/216;A61K31/22;A61K31/40;A61K31/4406;A61K31/4409;A61K31/445;A61K31/451;A61K31/495;A61K31/506;A61K31/5375;A61K31/5377;A61P35/00;A61P43/00;C07C49/84;C07C69/738;C07C205/45;C07C235/78;C07D213/40;C07D295/092;C07D295/185 主分类号 A61K31/4192
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