摘要 |
The present invention provides Hsp90 family protein inhibitors comprising, as an active ingredient, a benzoyl compound represented by general formula (I): (wherein n represents an integer of 0 to 10; R<SUP>1 </SUP>represents substituted or unsubstituted lower alkoxy, substituted or unsubstituted lower alkoxycarbonyl, CONR<SUP>7</SUP>R<SUP>8 </SUP>or the like; R<SUP>2 </SUP>represents substituted or unsubstituted aryl, a substituted or unsubstituted aromatic heterocyclic group or the like; R<SUP>3 </SUP>and R<SUP>5</SUP>, which may be the same or different, each represent a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl or the like; and R<SUP>4 </SUP>and R<SUP>6</SUP>, which may be the same or different, each represent a hydrogen atom, halogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl or the like) or a prodrug thereof, or a pharmaceutically acceptable salt of said benzoyl compound or said prodrug.
|