发明名称 |
COMBINATION COMPRISING ZD6474 AND AN ANTIANDROGEN |
摘要 |
The present invention relates to a method for the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation, particularly a method for the treatment of a cancer, particularly a cancer involving a solid tumour, which comprises the administration of ZD6474 in combination with androgen ablation; to a pharmaceutical composition comprising ZD6474 and an antiandrogen; to a combination product comprising ZD6474 and an antiandrogen for use in a method of treatment of a human or animal body by therapy; to a kit comprising ZD6474 and an antiandrogen; to the use of ZD6474 and an antiandrogen in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation. |
申请公布号 |
WO2006048633(A3) |
申请公布日期 |
2007.02.08 |
申请号 |
WO2005GB04220 |
申请日期 |
2005.11.01 |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;WEDGE, STEPHEN, ROBERT |
发明人 |
WEDGE, STEPHEN, ROBERT |
分类号 |
A61K31/517;A61K31/277;A61K38/09;A61K41/00;A61K45/06;A61P35/00 |
主分类号 |
A61K31/517 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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