PREPARATION OF ALKYLPIPERAZINYLPHENYL COMPOUND BY CLASSIC RESOLUTION

摘要

PROBLEM TO BE SOLVED: To provide a new method for optically resolving a racemic alkylpiperazinylphenyl compound containing a selective 5HT1Dantagonist. SOLUTION: The method is a new method for optically resolving a racemic alkylpiperazinylphenyl compound having formula I (wherein X, R1and R2are each specifically defined) and containing selective 5HT1Duseful in treatment or prevention of melancholia, anxiety, migraine, an obsessive-compulsive disorder (OCD) and other disorders for which 5-HT1agonist or 5-HT1antagonist is adapted. COPYRIGHT: (C)2007,JPO&INPIT