<p>An iontophoresis apparatus which comprises an electrolytic-solution holding part for holding a solution of an electrolyte which dissociates in solutions into a first electrolyte ion of the first conduction type and a second electrolyte ion of the second conduction type and, disposed on the front side of the electrolytic-solution holding part, a drug solution holding part for holding a solution of a drug which dissociates in solutions into a drug ion of the first conduction type and a drug counter ion of the second conduction type, the apparatus having a first ion-exchange membrane having first conduction type ion-exchanging groups introduced therein and a second ion-exchange membrane having second conduction type ion-exchanging groups introduced therein, these membranes being interposed between the electrolytic-solution holding part and the drug solution holding part.</p>